Marketing for Volkswagen Essay

Introduction The Volkswagen Group, one of world`s leading automobile manufacturers and the largest carmaker in Europe. The Group operates 48 production plants in thirteen Europe countries and a further six countries in the Americas, Asia and Africa. Around the world, more than 360,000 employees produce almost 25,400 vehicles or are involved in vehicle-related services each working day. The Volkswagen Group sells its vehicles in more than 150 countries. Recently years, global warming has become an international problem. The co2 from the vehicle is one of the most direct courses. Now, as the leader of the automobile manufacturers. Volkswagen pools all of its eco-friendly innovations under an umbrella brand that signifies efficiency: Blue Motion Technologies. This year, the vehicles labeled with Bluemotion tag is going to sell in eastern china and shanghai. Main body 1. Marketing concept of the Volkswagen Shanghai 1.1Original ideals A company always needs original ideals. Especially a big company like Volkswagen. The market changes everyday, people`s consumptive ideas changing everyday also. So, original ideals can help the company catch its old customers and attract new customers. 1.2 Be a civic-minded company Always pay more attention to the environment and do more public activities. Volkswagen is a big company, but also a part of the society. As a automobile manufacturer, should always pay attention to the environment. The vehicles it makes will produce much waste gas. So, pay attention to the environment protection can show the responsibilities of the society and its customers. 1.3Customer-focused Customer is the source of life of the company. A company always needs to take care of the customers. Give them best vehicles, never cheat them. Never let them lose the trust of the company. Good after-sell service is also needed. No one can promise the vehicle won`t have problem after the customer bought it. Fix it and a sincerely apologize can solve many unnecessary problems. Focus on the customer can also make a good benefit. For example, the Touran from Volkswagen has a good humanistic design. This car have a perfect order of its seats. The car itself is not big, but this design makes the space inside much larger than any cars in the same size. This makes Touran be the best choice for the middle class and makes a lot of money for the Volkswagen. 2. Market positioning Eastern China and shanghai is the richest place of China. This part produce the largest part of GDP in China. This is the best place to sell the vehicle with bluemotion technology. But not everyone in eastern China and shanghai will be interested. Here is the positioning of the market. 2.1 Market classify 2.1.1 Market in single people By the great economic growing in China, more and more people can by a private car. This would be a great market for the vehicle with bluemotion technology. 2.1.1.1 Classify by sex Most males have a great interested in the vehicle, a large part of them would like the big vehicle with a strong power. Many cars in Volkswagen, like Lamborghini. A supercar. Many men dreamed to have one. Females would be interest in a small and good looking vehicle. The Volkswagen Beetle`s streamlined outlook and colorful appearance is the best choice for a women. 2.1.1.2 Classify by age In technically, the Volkswagen car is suitable for very level of age, someone who can drive a car. But the main level is the people from 25 to 60, who have ability to buy a car by himself. So, the main market is the adult from 25 to 60. 2.1.1.3Classify by income The vehicles produce by Volkswagen are in the medium and high grade. The bluemotion technology is mainly use in the vehicles better than average. People with low income will not able to afford it. People with high income would like to buy the cars in top grate. So, people`s income between 5000-10,000RMB per month will be interest in the vehicle with bluemotion technology. 2.1.1.4Classify by the road condition Road condition is a major determinant of the vehicles. Road in downtown will be suitable for the vehicles produce by Volkswagen. Countryside is also all right, but not a best choice for it. 2.1.1.5Classify by the occupation Eastern China and shanghai have a large territory and have a big amount of occupations. Most occupations need a transport. Someone who lives away from his company will need a economical and environmental vehicle. The vehicle with bluemotion technology will be their best choice. Above all, a person, no matter a woman or a man, age between 20 to 60, who have a driving ability, can make money between 5000 to 10,000 per month, need a vehicle to go to work and live in a place with good road condition, will be the market of the Volkswagen`s car with bluemotion technology. 2.1.2 Market in public transport 2.1.2.1 Public transport is the mainly transportation in a big city. Most city in eastern China and shanghai have a mature public transport system. Includes: subway, bus, ferry, light railway and taxi. Bus and taxi should use the vehicle and the vehicles with bluemotion technology is the best choice for taxi. 2.1.2.2 Every taxi company have their own needed and choice. Vehicles from Volkswagen with bluemotion technology is suit for the companies which needs lower fuel cost, more steady fuel supply and of course ,better environmental protection. This technology make the car to use diesel oil and make the much lower oil consumption. It also provide lower co2. This is good for the environment . Above all, the taxi company which need needs lower fuel cost, more steady fuel supply and better environment protection will need the vehicle with bluemotion technology . 2.1.3 Market in collective Collective is a big market for vehicle selling. Almost every collective need some vehicles for transport. No meter a factor or a government department. 2.1.3.1 First, a collective should be a large collective that can afford the cost of the cars and the fuel the cars need. This a large money if there is a large amount of cars. 2.1.3.2 Second, the collective should have enough environmental awareness. The main aim of bluemotion is environmental protection. The collective which have environmental awareness will like to try the vehicles with this technology. 2.1.3.3 Third, the collective should have the wish to buy a car. Many collectives have saturated with the cars already. The Volkswagen should find out the collectives which still need cars. Above all, the collectives which have enough fund, environmental awareness and willing to buy a car is the main market for the Volkswagen. 2.2 Market positioning In the end, the main market for the vehicle from Volkswagen with bluemotion technology is: the people no matter a woman or a man, age between 20 to 60, who have a driving ability, can make money between 5000 to 10,000 per month, need a vehicle to go to work and live in a place with good road condition, the taxi company which need needs lower fuel cost, more steady fuel supply and better environment protection, the collectives which have enough fund, environmental awareness and willing to buy a car. Conclusion The Volkswagen should focus on the customers and always have original ideals. The market positioning is also very important. The Volkswagen should always know where the customers are and who is the customer. This will help the Volkswagen to sell the vehicle with bluemotion technology a lot. Reference http://auto.china.com http://www.vw.com.cn

Bowen Family Systems, Structural, and Strategic Models Essay

Bowen Family Systems, Structural, and Strategic Models Theory Application The case study of Ana will be analyzed using the Bowen Family Systems Theory Approach. Bowen Family Systems Theory is a theory of human behavior that views the family as an emotional unit and uses systems thinking to describe the complex interactions in the unit (Kerr, 2000). This paper will discuss the concepts of the theory that is appropriate for this case study; the reason this theory was chosen over the other ones; counseling goals and intervention strategies in accomplishing those goals; and designation of short or long term counseling. This paper will also discuss the counselor’s role with Ana; the client’s role in counseling; the population this theory is most appropriate for as well as addressing the social and cultural needs of the client; any additional information that might be helpful to know about this case; and what are the risks, if any, of using this approach. What concepts of the theory make it the most appropriate for the client in the case study? Include at least five concepts. There are five concepts that would make this theory appropriate for the client in the case study. The first concept in this Bowen Family Systems Theory Approach is triangles. What is a triangle? According to Kerr (2000), a triangle is a three-person relationship system. This triangle is a part of a bigger emotional system because a triangle is the smallest stable relationship system. These triangles involve, according to Murdock (2013), two people that are the â€Å"in† group and one person that is the â€Å"outside† group. Triangles form when the anxiety levels rise in a relationship or family (Titelman, 2008). Individuals (or families) with low levels of differentiation are more likely to triangle because more emotion is involved (Kerr, 1981). As a counselor, it is best to pay attention to your client and if they seem to react repeatedly to others, then you can suspect that a triangle has been activated (Murdock, 2013). As for Ana, there is a triangle  that has formed here. She is worried about surviving without her husband being around and figuring out how to make things meet because she is unemployed. The second concept of this theory is differentiation of self. According to Murdock (2013), differentiation deals with the individual as well as the family; however, according to Kerr (2000), the differences between an individual and family reflect the different levels of differentiation to self. A person who has low levels of differentiation are said to react and adjust their way of thinking to better suit the situation that they are in (Kerr, 2000). A person who has a high level of differentiation can keep their cool when conflicts arise (Kerr, 2000). Bowen (1978), refers a low-differentiated individual’s tendency to fuse as a â€Å"common self with others† and is most clearly seen in intimate relationships such as marriages. Titelman (2008), spoke of a pattern called underfunctioning-overfunctioning dynamic where the weaker individual in the family system is the weaker of the two and is more likely to develop symptoms. Ana is the weaker individual in the family since she does not have a job and she feels worried about how to continue with her life. She is hopeless and does not know what to do (Grand Canyon University, 2014). The third concept in this theory is the Nuclear Family Emotional Process. According to Kerr (2000), this concept describes four basic relationship patterns that govern where problems develop in a family. The four problems are marital conflict; dysfunction in one spouse; impairment of one or more children; and emotional distance. In a marital conflict, according to Kerr (2000), as family tension increases and the spouses get more anxious, each spouse ends up focusing on the negative issues about each other. In a dysfunction in one spouse problem, according to Kerr (2000), one spouse pressures the other spouse to think and act one way and then the other spouse yields to that pressure. If anxiety levels rise in these problems, psychiatric, medical, or social dysfunction may develop (Kerr, 2000). In impairment of one or more children problems, according to Kerr (2000), the spouses focus their anxieties on one or more of their children and the children focus their anxiety on them which can ultimately impair school performance, social relationships, and even health (Kerr, 2000). In emotional distance problems, according to Kerr (2000), people distances themselves from others to reduce the intensity of the relationship, but risk  isolation from each other. The fourth concept of this theory is the family projection process. This concept describes the primary way parents transmit their emotional problems to a child (Kerr, 2000). This process can impair the functioning of one or more children and can increase their clinical symptoms. Some problems that children inherit from their parents include the need for attention and approval; difficulty dealing with expectations; the tendency to blame oneself or others; feeling responsible for the happiness of others or that others are responsible for one’s own happiness; and acting impulsively to relieve the anxiety of the moment rather than tolerating anxiety and acting thoughtfully (Kerr, 2000). Parents have different roles in this process: mothers are the primary caretakers and experience more emotional involvement with one or more child and fathers experience the outside of the triangle, except in high level of tensions among the mother and child (children) (Kerr, 2000). Even though Ana’s son is only one years old, problems may arise in him later on in life because of the problems going on at home right now and with the father being deployed. The fifth concept of this theory is multigenerational transmission process. This process describes how small differences in the levels of differentiation between parents and their offspring lead over many generations to marked differences in differentiation among the members of a multigenerational family (Kerr, 2000). Why did you choose this theory over the others? The Family Systems Theory was chosen for the evaluation of Ana’s case study because this theory focuses on the family not just the individual alone. Even though Ana went in for a counseling session alone, there are underlying issues that most likely involve her family as well. What will be the goals of counseling and what intervention strategies are used to accomplish those goals? The goal of the Bowen Family Systems Theory (BFST) is to help an individual or individuals separate from the family (Titelman, 2008). According to Murdock (2013), an individual must remember that this separation does not mean that he or she needs to cut their family from their life. This theory should help an individual alter the way they reactive in relationships and change the way they handle stress (Murdock, 2013). There is an intervention strategy that can help accomplish the goal of the BFST. This strategy is process questioning. According to Murdock (2013), the questions that are asked help an individual avoid the emotion that is associated with content questions. Is the theory designed for short- or long-term counseling? The BFST is designed for long-term counseling. Treatment of an individual can potentially take years to complete, however, it does depend on the individual and well they advance and overcome their treatment goals (Withers, 2012). What will be the counselor’s role with this client? A BFST counselor remains detriangled in this type of counseling session by presenting themselves as objectively and unemotionally (Kerr, 1981; Murdock, 2013). The counselor is there to teach the client about the operation of family systems (Murdock, 2013). In order to effectively treat an individual, according to Murdock (2013), a counselor should undergo their own BFST therapy himself. What is the client’s role in counseling? In a BFST counseling session, a client is assigned the task of journeying home to observe family interactions; put the principles that were learned into effect; and change how he or she interacts with the family (Murdock, 2013). For what population(s) is this theory most appropriate? How does this theory address the social and cultural needs of the client? BFST is contrary to the norms of many cultures because they tend to support separation of individuals and families (Murdock, 2013). BFST approaches cannot really treat close-knit Latino families or African-American families because of their close family relationships with one another (Sue & Sue, 2008; Falicov & Brudner-White, 1983). What additional information might be helpful to know about this case? Some additional information that might be helpful to know about this case is how Ana feels about bringing her family in to counseling sessions to see if there are any underlying issues that need to be resolved. What may be a  risk in using this approach? After researching this theory, â€Å"some aspects of this theory seem to be operationalizable and testable† (Murdock, 2013, p. 451). Even empirical tests of the BFST have produced promising results in areas such as relationships among differentiation; anxiety; relationship satisfaction; and psychological dysfunction (Murdock, 2013; Miller, Anderson, & Keala, 2004). Bowen’s prediction of individuals choosing partners with similar levels of differentiation received mixed results in the literature, with studies confirming and others disconfirming (Murdock, 2013; Day, St, Clair, & Marshall, 1997; Greene & Mabee, 1992; Kosek). However, when BFST is dealt with family or couples processes, research is less supportive. The Bowen Family Systems Theory was the theory chosen for this paper to analyze the case study of Ana. This paper discussed the concepts of the theory that is appropriate for this case study; the reason this theory was chosen over the other ones; counseling goals and intervention strategies in accomplishing those goals; and designation of short or long term counseling. This paper also discussed the counselor’s role with Ana; the client’s role in counseling; the population this theory is most appropriate for as well as addressing the social and cultural needs of the client; any additional information that might be helpful to know about this case; and what are the risks, References Bowen, M. (1978). Family therapy in clinical practice. New York: Jason Aronson. Day, H. D., St. Clair, S., & Marshall, D. D. (1997). Do people who marry really have the same level of differentiation of self? Journal of Family Psychology, 11 doi: 10.1037//0893-3200.11.1.131 Falicov, C.J., & Brudner-White, L. (1983). The shifting family triangle: The issue of cultural and contextual relativity. In J.C. Hansen & C.J. Falicov (Eds.). Cultural perspectives in family therapy. Rockville, MD: Aspen Systems. Greene, G.J., & Mabee, T. F. (1992). Differentiation of self and marital adjustment of clinical and nonclinical spouses. In B.J. Brothers (Ed.), Couples therapy, multiple perspectives: In search of universal threads. New York: Haworth Press. Grand Canyon University (2014). Case study analysis. Kerr, M.E. (1981). Family systems theory and therapy. In A.S. Gurman & D.P. Kniskern (Eds.), Handbook of family therapy. New York: Brunner/Mazel. Kerr, Michael E. (2000). One Family’s Story: A Primer on Bowen Theory. The Bowen Center for the Study of the Family. Retrieved from http://www thebowencenter.org/theory Miller, R.B., Anderson, S., & Keala, D.K. (2004). Is Bowen theory valid? A review of basic research. Journal if Marital and Family Therapy, 30, doi: 10.1111/j.1752.0606.2004.tb01255.x Murdock, N. (2013). Theory Is a Good Thing. In Theories of counseling and psychotherapy: A case approach (Third ed., p. 4). Upper Saddle River, N.J.: rill/Prentice Hall. Sue, D. W., & Sue, D. (2008). Counseling the culturally diverse: Theory and practice (5th Ed.). Hoboken, NJ: Wiley. Titelman, P. (2008). The concept of the triangle in Bowen theory: An overview. In P. Titelman (Ed.), Triangles: Bowen family systems theory perspectives New York: Routledge. Withers, R. (2012). A comparative study of Bowenian system theory and cognitive-behavioral family therapy. Retrieved from http://www.counselinginsite.com

LACMA Museum Visit Essay

The third floor of the Los Angeles County Museum of Art houses a permanent collection on Ancient Egyptian art. One of the pieces there is a 13†³ high figurine of the goddess Wadjet, sculpted from bronze in during the 26th Dynasty, est. 664-525 BCE. The figurine is in the round, with only the goddess’s feet attached the rectangular base she stands on. The hieroglyphs on the base identify her, as well as the name and parentage of the person who dedicated her figurine. She is shown in the traditional ancient Egyptian pose, with her left foot forward. She is wearing some sort of dress, but her decidedly feminine figure, with a curved abdomen, narrow waist, and protruding breasts, is clearly portrayed through it. Her right arm is held rigidly at her side, again in strict stylistic convention, and her left arm bends only at the elbow to hold whatever less enduring material was placed there. In fact, both of her hands were clearly intended to encircle props, but these have been lost and as such, what they once were can only be inferred from other portrayals of the goddess. She clearly wears necklaces, armbands, and bracelets; this highly detailed work is also present on her lion’s mane, which is shaped similarly to the pharoah’s headdress. She has the head of a lioness, upon which rests the sacred cobra and sun disk, called the uraeus. The goddess Wadjet was emblematic of Lower Egypt- she was often portrayed with her counterpart in Upper Egypt, Nekhbet, handing their joint power to the pharaoh of the time. Other than those human depictions, she was usually shown as a cobra, which allows this piece to be dated- she was only pictured with the lioness head after her mythology was merged with that of Bast, the war goddess of Lower Egypt, in the Late Dynastic period. (source?) As a symbol of Lower Egypt, it can be surmised that she was holding a papyrus  scepter in her left hand, and an ankh in her right. These figurines were commonly bought by wealthy patrons visiting temples. They often had the remains of animals inside them. Put more stuff here. Sources: _Figurine of the Goddess Wadjet_. 664-525 BCE. Los Angeles County Museum of Art, Los Angeles. Watterson, Barbara. _Gods of Ancient Egypt_. 1984. Godalming, Surrey: Bramley Books Limited, 1999.

Research-week11 Essay Example | Topics and Well Written Essays - 1500 words

Research-week11 - Essay Example Teachers can improve children’s attitudes toward school, behavior at school, and academic achievement through the use of effective methods of directions and management. Researched effects of programs offered to teachers, parents, and children. The gap that I see is the application of the social factors in isolation and the extent of impact they have on juvenile behavior being explained by the use of the social learning theory. Also one can achieve a much superior understanding of the individual, societal and psychological aspects of juvenile delinquency. Theory/Theories or Conceptual Framework(s) Related to the Area of Inquiry: The theory that I plan on incorporating in my research is the Social control theory. Social control theory refers to a perspective which predicts that when social constraints on antisocial behavior are weakened or absent, delinquent behavior emerges. Rather than stressing causative factors in criminal behavior, control theory asks why people actually ob ey rules instead of breaking them. This theory stresses the idea that people in a society commit delinquent or criminal acts because of the weakness of the forces restraining them, not because of the strength of forces driving them to do so. It asserts that social controls, like arrest, imprisonment, loss of income, etc. increase the costs of violent behaviors (Psychology glossary). Purpose of Your Research: The purpose of this research paper will be to investigate the social causes of violent juvenile crime. The social elements examined will be that of domestic violence, substance abuse, peer pressure and perhaps media exposure. The social control theory will aid in the explanation and examination of these factors and together accumulate to enhance our understanding of how dire the impact of social elements on today’s youth’s ability to commit crimes is. Your Proposed Research Approach/Methodology: Mixed method research. Describe Your Proposed Design: The mixed method research design that suits research into my area of interest is sequential explanatory strategy. Similar to sequential explanatory strategy, it is conducted in two phases. However this strategy is characterized by the collection and analysis of qualitative data followed by the collection and analysis of quantitative data. In turn, priority is given to the qualitative aspects of this study. The purpose of this strategy is to use quantitative data and results to assist in the interpretation of the qualitative findings (Knowledge base, web). Proposed Research Population and How You Would Draw Upon this Population for your Research Inquiry: Under 18 boys and girls with a juvenile record, who are primarily high school students and belong to the American culture. The method of non probability sampling I believe will be most appropriate for carrying out my research. In fact to be even specific purposive sampling technique which aids exploratory research and encompasses obtaining data from specific individuals, in case of my investigation this would be juveniles. This will ensure internal validity of the study as the chosen sample will be a certain fraction of the population. With the help of self report surveys; questionnaire or poll participants will select a response by themselves without researcher interference. Examples of Research Data

US and the first World War Essay Example | Topics and Well Written Essays - 1250 words

US and the first World War - Essay Example The reason why America had to employ isolationism policy during the world related to the fact that majority of the America population are immigrants with some originating from the battling Austria-Hungary and Germany. This escalated the impossibility of America intervening for favor of its historic friend Britain because many people claimed that they had certain connection with the three anti-British countries. Besides the outcry by sections of the America as having particular links with Germany and Austria-Hungary, America also objected to take the neutral position to encourage its commercial deals with all the European countries. This was irrespective of whether the trading partner was pro or anti Britain. In 1898, America and Spain got into fierce war a move that seen to be the quest by America to expand its territories. Prior to the outbreak of the war between America and Spain, there were widespread of cries and revolt by Cuban people who wanted to secure their independence from Spain. As demonstrated by Morreta and Kearney, the Spanish government oppressed the Cuban civilians and news spread across America to trigger public anger (145). The government of US through the approval of President William McKinley made peaceful calls on Spanish government to withdraw from Cuba. ... cted by Americans was due to the past painful experiences of the Civil Wars, that just preceded the Great War and that saw massive exhaustion of the war equipments and a reduced military force. However, Spanish government refused the calls and in fact moved on to sink American battleship. This triggered tension in America, and the government deployed soldiers and war equipments to attack Spanish government through both the Pacific and Caribbean Oceans. According to Morreta and Kearney, the first field of war for the American-Spanish battle was in Philippines (146). After four months of serious battle, America forces appeared to overwhelm the Spanish forces thus paving the way for the surrender. Surrendering by the Spanish forces led to the brokering of peace deal that led to the Treaty of Paris signed in 1899. It is in this war that America appeared as the world’s superpower. The silence and isolationism policy adopted by government of US came to end during the World War I. Th is happened even when America objected to maintain neutrality despites the aggression of German on Britain and France. The World War I was going to result from various factors like militarism where countries like Germany, Britain, France and Russia wanted to dominate each other on the basis of strong military bases. Escalation of the war was due the existence of many alliances formed mainly to help individual parties to strengthen their defense. For instance, Russia had established alliance with Serbia, Russia with France, Japan with Britain, France with Britain and Belgium, and Germany with Austria-Hungary (Morreta and Kearney 148). When the war began, members of a particular alliance or connected with particular common country would merge to fight the common enemy. Another cause of the WWI was

Concentrated Solar Power Essay Example | Topics and Well Written Essays - 1500 words

Concentrated Solar Power - Essay Example The second chapter introduces us to possible solution to the problem stated in the introduction chapter. In the third chapter, various aspects of the solution are analyzed. In this case, the research has clearly explained justifications for using the solution outlined. The conclusion gives a summary of main ideas outlined in the research. In addition, various recommendations have been presented for potential advancement of this technology. We have analyzed various ways through which the lighting problem in the rural areas and other areas that are not connected to the grid can be lighted up. In addition, we have been focussing on the ways that can be adopted in order to in the installation scale down the electricity bills payable by consumers for the power supply. One of the main openings to providing a solution for the stated problems is to utilize the solar energy. It is important to note that every single household is always connected to the solar energy; since it is freely availab le as a gift of nature. This report investigates a power system used to generate electricity for powering domestic holdings, business and industries. The essay makes various recommendations for effective installation of solar panels to ensure that maximum power will be produced. In addition, this work provides technical skills for technicians involved in the installation. This research has been conducted with the aim of unmasking the potential that the solar energy possess if it was fully exploited.

Employment Law-Conflict Management in Organizations in paticular Essay

Employment Law-Conflict Management in Organizations in paticular countries - Essay Example Thus, conflict management strategies at the workplace aid to create a healthy and productive work environment. In light of this, the paper will evaluate and analyse conflict management strategies in Australia, China, the United Kingdom, Japan and New Zealand. Primarily, avoidance, litigation, negotiation, mediation, conciliation and arbitration are the major dispute resolution methods globally. Further, mediation, negotiation, conciliation and arbitration are all grouped under alternative dispute resolution methods (ADR). These methods aim to ensure and advance equity (justice and fairness), efficiency (effective utilisation of limited resources) and participation/inclusion in decision making at the workplace. On the other hand, there are basically two types of conflicts; collective and individual conflicts. In the United Kingdom, there is a drastic decrease in collective action. Therefore, strike actions and use of unions is on the decline. Collective conciliation has for more than 100 years been part and parcel of the workplace/industrial relations setting. However, its application in dispute resolution between employers and groups of employers in the United Kingdom has been on the decline. Its popularity has been affected by an increasing experience of employee representatives and Human Resource, the current nature of trade unions and the statutory employment framework-the main players in collective conciliation (Colquitt, Jet al. 2001). Consequently, there has been a rise in an individualistic approach to conflict resolution. Individualism unlike collectivism which places more value on the group, places more significance on the individual’s interests. Therefore, individual arbitration is becoming more embraced in the United Kingdom than in the past where collectivism was a mo re preferable approach. Also, human resource managers in organisations presently tend to solve most individual conflicts at the workplace in the United Kingdom (Tinsley, C.

Given likely changes to the operating environment, analyse how UK air Essay

Given likely changes to the operating environment, analyse how UK air power might be most effectively employed over the next 10 years - Essay Example They have served to only protect air interested over the United Kingdom, but its many allies around the globe as well. When called upon, the Royal Air Force has done what it can to lend assistance. The future, however, will see many of the mechanisms by which air power is facilitated change, while the core function of protecting and defending will remain the same. While the past has demonstrated the effective of the air power inherent within the structure of the United Kingdom, such as their ability to assist allied forces in the war in Afghanistan, the reality is that the future will likely look much different. That is the focus of this concise report. It has been stated that, for the Royal Air Force to continue at its current level of effectiveness, it will need to enhance its partnerships with allies in order to deliver the air power necessary to defend domestic interests into the middle part of the 21st century. The future of air power in the United Kingdom, then, will likely involve partnerships with various interests, both internationally and domestic (Blount, 2009). These partnerships will be with both military and civilian organizations, and from a combination of government and industry interest groups. In this age of increasing global military technology, in conjunction with ever growing threats from various terrorist organizations that would seek to harm UK interests, these partnerships are quickly becoming vital to ensuring the effective delivery of air power in terms of UK interests moving forward in the 21st century. The future will involve the increasing importance, for example, of engaging in space and cyber technolo gy as a means of further refining the overall strategy relating to air power, both within the borders of the United Kingdom, and beyond (Blount, 2009). . Technology is already serving to reshape how the UK views it propensity

Corporate Finance Nautilus Research Paper Example | Topics and Well Written Essays - 2500 words

Corporate Finance Nautilus - Research Paper Example The appropriate discount rate is 6.04%, which is the weighted average cost of capital. The present value of the firm with this discount factor and the predicted cash flows is $12,885,000. Introduction Nautilus Inc. is a Consumer Fitness Products Company founded in 1986 and headquartered in Vancouver, Washington. The company was incorporated in 1993 in the state of Washington. The company targets individuals and enthusiasts who wish to enjoy the benefits of regular exercise and thereby improve their health. The company sells its products through two channels – direct and retail. The main objective of corporate finance is to maximize the value of shareholders by making proper investment and financing decisions. This paper examines the extent to which Nautilus has been successful in meeting this objective, and whether the stocks of the company represent a safe and worthwhile investment. Observations In order to evaluate the performance and financial status of the company, some of the important financial ratios, trends and market information were collected and analyzed. Some of the important financial figures for a period of five years between 2007 and 2011 are shown in Appendix-1. Relevant ratios have been calculated and are shown in Appendix-2. Sales The growth in sales for the year ended December 31, 2011 was 7.1% over the figures of 2010. However, for the three preceding years the growth has been negative. The trend has been good, and in each year the negative growth has been reduced, and the growth rate has become positive in 2011. The company operates in two segments, namely direct sales and retail sales. The segment wise sales figures for the years 2010 and 2011 are shown in Table-1. It can be seen that direct sales constituted almost 60% of the total sales, while retail sales made up the remaining 40%. A small portion of the total income has come from royalty. A look at the distribution of the sales shows that cardio products accounted for the major portion of the sales accounting for 42% of the direct sales in 2011 and 32% in 2010. Overall, cardio products accounted for 66.35% in 2011. Cardio products have also shown a healthy growth in direct sales but a small decline in retail sales. Strength products accounted for 31.02% in 2011. Percentage of Total Year Ended December 31, 2011 2010 Change % Change 2011 2010 Direct net sales: Cardio products (1) $75,982 $54,409 $21,573 39.60% 42.12% 32.30% Strength products (2) 31,079 42,259 -11,180 -26.50% 17.23% 25.09% Total Direct net sales 107,061 96,668 10,393 10.80% 59.34% 57.39% Retail net sales: Cardio products (1) 43,718 43,628 90 0.20% 24.23% 25.90% Strength products (2) 24,873 24,161 712 2.90% 13.79% 14.34% Total Retail net sales 68,591 67,789 802 1.20% 38.02% 40.24% Royalty income 4,760 3,993 767 19.20% 2.64% 2.37% Total net sales $180,412 $168,450 $11,962 7.10% 100.00% 100.00% Table-1 Distribution and Growth of Sales1 Equity Growth and Profitability Equity investors are concern ed primarily with the return on their investment and the growth of their wealth. Various profitability ratios and equity growth are showninTable-2 Profitability 2011 2010 2009 2008 2007 Return on

Methods of Research Paper Example | Topics and Well Written Essays - 3250 words

Methods of - Research Paper Example Approximately 76% of firms in different geographical areas use social networking to achieve their marketing strategy. Retailers have achieved 133% increases in profit through the mobile market and thus they promote social media. An approximated 40% of United States shoppers usually use their Smartphone to buy products online and thus becoming a need than a want. There is a gap that exists while investing in social media marketing. Messages are shared in the social network concerning the brands and services offered by a certain firm and thus they are passed from user to user. This means that the company only posted once in the site for example, in the Facebook which has millions users. The messages and images of the brands are available to the third person without his or her request that he or she wants the brands but they are going to be posted. This means that the firm that posted the brands once does not need to keep on monitoring who has been interacting with their site. Through t he use of social media they can use the strategy of winning a prize or the first individual who can share and like the brands in the firm can win a prize or get the brand of his or her choice at a discounted rate. This is a gap that many companies have never thought about it but play a significant role in social media marketing. Based on the research done by Mangold and Faulds (2009), though investing in social media is costly, it plays a significant role in marketing for example, brand awareness is attained. Social media is a tool that creates competition in the market since different companies use the technology to advertise their products through such media. For example the use of Facebook, YouTube, twitter, Google and LinkedIn among others. One of the notable aspects to note while educating an individual who want to use social media marketing is that it is generally expensive. However, in reality it plays a significant role in making sure that awareness of the

Honda in Europe Case Study Example | Topics and Well Written Essays - 2250 words

Honda in Europe - Case Study Example The paper tells that the issue of cultural diversity, in regards to international marketing, is of utmost importance. It is, therefore, critical for Honda to treat the culture of each country in its own context. Furthermore, different countries from the European region have different cultural values, which significantly affect their thinking behaviors and actions. Honda appears to have made a grave cultural mistake while designing its global marketing strategy and, therefore, it will be very wise to understand the cultural practices and values of each country and design strategies that resonate the individual’s country’s culture. The poor performance of Honda in Europe has been thought to have resulted from the failure of the company to understand the culture of European countries and instead treating the market as a homogenous block. The differences amongst different European countries have been split between high-context versus low-context cultures – Honda ough t to design its marketing strategies to be in line with these cultural divisions, to enhance acceptability of its products in the respective countries. Ideally, Honda ought to have understood that the kind of advertisement that is suitable for low context cultures is different from that which is suitable for high context cultures. In essence, the advertisement for high-context culture should encompass an embedded approach where the weight is put on the general view and feel instead of providing the literal information.... In conclusion, it is not wise for Honda to market its products the same way in all countries because it is improbable that an advertisement intended for a low-context culture will work in a high-context culture and vice versa. Given that Europe is a multicultural block, Honda should take into account the two cultural segments when designing a market strategy. Is it wise for Honda to market its products the same way in every country? It is not wise for Honda to enter the global market with a similar strategy in every country because, actually, this is the mistake the company committed, in the past, leading to poorly performance in different regions especially in Europe. It is important to pay attention to various political, social and economic forces that influence business in different countries and design strategies that resonates to those factors. These factors are very essential because they are used to define the decisions to take when producing, selling and delivering products a nd services to consumers from different parts of the world. Honda should carefully assess the style, taste, culture and values and believes of its customers from different countries because these factors are essential when designing an international marketing plan. For instance, Honda should apply marketing mix that is unique to individual countries, based on factors such as language barrier, economic circumstances among many others. Socio- economic considerations, technically, are important factors that influence the company’s taxation, transport cost, people’s taste and needs as well as the competition from other companies. From the statistics, Honda is facing stiff competition from different regions, especially the

English-language films Essay Example for Free

English-language films Essay Working as a congressional page, I was given the ability to manage my academic success through my own initiative. Dealing with independence was a revealing experience for me, giving me new responsibilities and shaping my work ethics. I didn’t have my parents, now 5,000 miles away, to urge me to finish my homework or to nag about my less than perfect grades, and I couldn’t depend on the support of the teachers or counselor that I knew so well to look after my academic well-being. There was a realization that I was alone in my struggle to succeed and become a responsible student. This independence allowed me to take the situation into my own hands and to work out my own problems, knowing I was the dictator of my consequences and decisions. In this situation, I learned how to set my priorities, a skill that has taken me a step toward preparing for college. Knowing that education would provide the foundation for my future in college and beyond, I placed it at the top of my values, so even in the excitement of new friends and complete independence, I had to maintain it as my first priority. Though it proved difficult to discipline myself without support and accountability alone, I managed to succeed. I’d invite friends over to my room to study, and it eventually became a custom to for us hold study sessions in my room every Monday night and before test days. The entire night was devoted to completing our assignments, studying for exams, and tutoring each other. After the strenuous study session, we’d reward ourselves with a movie and light conversations. These study sessions were an efficient way in which I could balance two of my important priorities, friends and academics. Living on my own and balancing a hectic load of school, work, and dorm life, I gained insight in effectively managing my own time, which was essential in preparing myself for academic success. It wasn’t a rare occurrence for Congress to stay into the thick hours of the morning, debating over a controversial issue, such as the budget or immigration. During these nights, I was required to wait on congressman on the Floor and carry out errands late into the night. Working late did not give us amnesty from the school’s assignments, so we had to make the most use of whatever time we had. Working as a page obviously cut into the precious time I had to concentrate on my school work, forcing me to partition my time wisely. It became an unsaid rule for me to sign myself into an hour of study hall every week night, so that I wouldn’t be distracted by roommates or requests to go out. I had an excuse to delay my friends’ invitations to the movies or to the mall until I felt confident I could do my best on the pre-calculus or history test we would have on Friday. With my packed schedule, I spent my time wisely to get the most out of my experience in Washington, while maintaining my grades and academics. The independence that I was fortunate enough to experience for the first time exposed me to responsibilities has helped me to prepare for college. It has disciplined me to set my priorities and manage my time to be the most effective student possible. Like a young eagle learning to fly, I learned to steer myself in the right direction. And so, I landed a more prepared and experienced person.

Dissolution Profile of Paracetamol Generics

Dissolution Profile of Paracetamol Generics 1 Introduction The pharmaceutical industry had an estimated turnover of $773 billion in 2008,1 however not all of this revenue was taken as profit; a significant cost goes into research and industry guideline compliance. With regards to new generic medications, proving bioequivalence is crucial to success, however necessary in vivo testing can be costly.2 Drugs which meet certain Biopharmaceutics Classification System (BCS) criteria may be exempt from these expensive tests and can be permitted a biowaiver.3 This allows in vitro dissolution testing in place of in vivo plasma analysis. Paracetamol is one such drug that has qualities which place it at the borderline of biowaiver suitability.3 It is the worlds most commonly used analgesic4 and the question arises as to whether all preparations are as effective as each other? More specifically we ask, is there is any significant difference between the dissolution profile of paracetamol generics? This literature review is in preparation of experimental t ests designed to ascertain if there is any difference in dissolution profile of eight bioequivalent preparations listed on the Australian Pharmaceutical Benefits Scheme (PBS), and whether this difference may correlate to a clinical significance in such a common place drug. 2 Search Strategy All data was sourced through internet databases, i.e. Medline, Pubmed, and the Cochrane Library. The search engines Google Scholar and UWA library were also utilized. Keywords included. KEY WORDS Paracetamol, acetaminophen, bioequivalent (therapeutic equivalency), Delayed-action Preparations, Pharmaceutical Preparations, Tablets, Drug Compounding, Chemistry, Pharmaceutical, Observer Variation, Dissolution, Metabolism, in vitro, in vivo, IVIVC, Drug Content, Bioavailability and Correlation. Boolean searching was utilised to broaden or narrow search results and once appropriate articles were sourced, citing and cited articles were also evaluated. 3 Paracetamol 3.1 History Paracetamol (acetaminophen) is one of the worlds most popular drugs for the treatment of pain and fever.4 It was first synthesized in 1878 by Morse, and was used clinically for the first time in 1887 by von Merring.4, 5 Paracetamol fell into obscurity shortly thereafter in favour of other chemically related drugs such as phenacetin.5 However, phenacetin was later found to be nephrotoxic, and the search for a substitute arose.5 In 1950, a study from Brodie and Axelrod rediscovered paracetamols suitable analgesic properties.4 Although, this drug did not experience widespread acceptance until the 1970s due to unfounded concerns about safety; but from then on, it became the most commonly used medication for pain.4 In many countries, such as the United Kingdom, paracetamol sales have exceeded those of aspirin since 1980.4 3.2 Physicochemical properties Paracetamol or N-(4-hydroxyphenyl) acetamide, is a white crystalline powder with a melting point of 168-172C (Martindale). It is sparingly soluble in water, ie. one part of paracetamol is soluble in 70 parts of water at room temperature.3 It is also freely soluble in alcohol. (Martindale) Paracetamol shows maximal UV absorption at a wavelength of 249nm and is reported to have a pKa of 9.5 at 25C.3 3.3 Pharmacology Pharmacokinetics 3.3.1 Pharmacodynamics Mechanism of Action The exact mechanism of action of paracetamol has remained largely unknown for some time.6-9 For years it has been thought to inhibit the enzyme cyclooxygenase (COX) in a similar manner to non-steroidal anti-inflammatory drugs, however definitive proof of analgesia and antipyresis being dependent on COX inhibition is still lacking.4 Recently, two independent groups have produced experimental data that has demonstrated that analgesia involves the potentiation of the cannabinoid vanilloid tone in the brain and in the dorsal root ganglia.4 Blockade of cannabinoid (CB1) receptors in rats has eliminated any analgesic properties of paracetamol and suggests that paracetamol is in fact a cannabinomimetic.4 3.3.2 Pharmacokinetics 3.3.2.1 Absorption Bioavailability: Paracetamol has been reported to have a bioavailability of 62%-89% in those of a fasted state,3, 8 this divergence from absolute bioavailability is attributed to first pass hepatic metabolism. Peak plasma concentrations are reached between 0.17-2.0 hours post-dosing.10 As expected, food has been shown to reduce absorption by increasing tmax and decreasing Cmax values. Food has not been shown to affect the amount of acetaminophen reaching the blood.3 3.3.2.2 Distribution: Paracetamol has a reported volume of distribution of 0.69-1.36L/Kg.11 Around 20%-25% of the drug is bound to plasma proteins at therapeutic dosages; however this value has been shown to increase to 20%-50% in over dosage. Paracetamol has also been shown to cross the placenta, and has a 1.24 milk/plasma ratio in breast milk.3 Paracetamol is an ADEC category A drug, i.e. it is safe to use in pregnancy, as well as breastfeeding.9 3.3.2.3 Metabolism Excretion: Around 85%-90% of paracetamol is metabolized within the liver via the process of glucuronidation and sulfation.3 These inactive metabolites are then eliminated by the kidney in the urine. Approximately 5% of paracetamol is passed out unchanged in the urine, the remaining drug is conjugated with cysteine and mercapturic acid.3, 8 The half-life of paracetamol has been reported as 1.9 4.3 hours3, 8, 10 but longer in those with renal impairment. 3.4 Indication Paracetamol is indicated in the symptomatic treatment of mild-to-moderate pain as well as fever3, 9 and has also been described to have mild anti-inflammatory properties.3 3.5 Dose Dosage Forms For adults, the optimal single dose of paracetamol is 1g,3, 9 with a maximum dose of 4g daily.9 Hepatocellular necrosis can occur from doses of 10-15g, and death may result in doses in excess of 20-25g.3 Paracetamol is available in many dosage forms, as a single active pharmaceutical ingredient (API), or in combination with other analgesics such as codeine (Panadeine), dextropropoxyphene (Di-Gesic), metoclopramide (Metomax), as well as in combination with decongestants such as pseudoephedrine in cold-and-flu preparations.9 This drug is available as immediate release (IR) tablets, sustained release (SR) tablets, chewable, elixirs, IV injections and suppositories.9 4 Biopharmaceutics Classification System The Biopharmaceutics Classification System (BCS) is a method of grouping active pharmaceutical ingredients (API) based on their solubility and intestinal permeability.12-16 The system allows for easy identification of those drugs whose in vivo absorption can be easily anticipated based on their in vitro dissolution.12, 15, 16 This implies that two different products containing the same drug will have the same rate and extent of absorption if, over time, they both have the same concentration profile at the intestinal membrane.12 Since it is the dissolution profile of a drug which determines its concentration profile in the intestinal lumen, comparability of this parameter in vitro should produce comparable absorption results in vivo.12 In reality however, only those drugs with high permeability which are formulated into IR preparations can be easily and reliably applied to this logic.12, 15, 16 4.1 BCS Drug Classes There are four classes within the BCS to which a drug can be assigned (as outlined in figure 1). Class I is comprised of those drugs with high permeability and solubility, these drugs are expected to be well absorbed and, providing dissolution is slower than gastric emptying, show a good correlation between in vitro dissolution rate and the rate and extent of in vivo absorption (IVIVC).12, 15, 16 Class II drugs also have high permeability but their solubility is low which ensures in vivo dissolution is the rate limiting step in drug absorption and thus IVIVC is expected.12 Class III drugs have a low permeability with high solubility, traditionally these drugs were believed to have little or no IVIVC,12 however recent studies have shown that if a class III drug is very rapidly dissolving then a correlation may exist.18, 19 Finally Class IV drugs have both low permeability and solubility these drugs are not expected to show any IVIVC.12 For each of the four BCS classes a drug substance is considered highly soluble when the highest [IR] dose strength is soluble in 250mL or less of aqueous media over the pH range of 1-7.5.16 The permeability of a drug is considered high if greater than 90% of a dose is absorbed across the intestinal membrane.16, 20 Using these definitions, paracetamol is classified as a BCS class III drug but it is also described as borderline class I because it is only just on the cusp of low permeability.3 4.2 Utility of the BCS The genius of the BCS is that it allows easy identification of drug candidates for which relatively cheap and fast in vitro dissolution testing can replace the more expensive, time consuming and invasive in vivo absorption testing.2 The system does away with complex bioavailability modeling that must account for fasted and fed states as well as cyclical changes in motility and gastric emptying.12, 14 The impact of the BCS on the pharmaceutical industry was so great that in 2006, creator Dr. Gordon Amidon was awarded the International Pharmaceutical Federation (FIP) Distinguished Scientist Award.21 5 Correlation between in vitro dissolution and bioavailability Following the introduction of the BCS a great deal of research was conducted exploring the power of IVIVC. It became a main focus not just of the pharmaceutical industry but also of academia and regulatory authorities.2 IVIVC became popular because it can be used as a substitute for resource intensive bioavailability testing; the concept has essentially improved the speed and cost of drug development as well as quality control in pharmaceutical manufacturing.2 5.1 Bioavailability and Bioequivalence Bioavailability is an important concept because it determines the efficacy, safety and reproducibility of the therapeutic effect of drugs and the many formulations in which they come.22 For the purpose of drugs that produce a systemic therapeutic effect, the Australian Therapeutic Goods Administration (TGA)22 defines bioavailability as the extent and the rate at which a substance or its active moiety is delivered from a pharmaceutical form and becomes available in the general circulation. Bioavailability is therefore inherently linked to drug absorption and may also be predicted using IVIVC as defined by the BCS. If two pharmaceutically equivalent (same active ingredient and content in the same formulation) products have the same bioavailability they are considered bioequivalent and will essentially have the same efficacy and safety. Bioequivalence is important because it is the basis for which innovator medicines can be substituted with generics. 5.2 Strength of in vitro in vivo correlations The BCS is a predictive tool for determining which drugs will have an IVIVC. Table 1 demonstrates that under the BCS only class II along with some class I drugs are expected to have IVIVCs.12 Research subsequent to Dr. Amidons first BCS publication has generally upheld his initial findings however exceptions to the rule have been found. 5.2.1 Drugs with IVIVC The BCS suggests that if the bioavailability of a drug is dissolution rate limited then a good IVIVC should be possible. This notion has been demonstrated for flutamide a very poorly soluble high dose compound which is not expected to have IVIVC but has dissolution rate limited absorption.23 A paper published by Posti, Katila Kostiainen23 concluded that there is a strong IVIVC for flutamide and this was identified on four separate occasions where bioavailability was studied. All four studies were of single dose, cross over design and each subsequent study increased the number of subjects tested (study I: n = 6, Study IV: n = 24). The strength of the papers methodology provides good support for its conclusions however this was undermined by a lack of documented statistical analysis. Much more compelling evidence comes from a study by Sakuma et. al.24 which was able to show an IVIVC for two BCS class I drugs after they received an enteric coating, thus eliminating the possibility that gastric emptying was the rate limiting step. The results were statistically significant, however the tablets were tested in rat models rather than human subjects and the dissolution test may not have adequately reflected the in vivo environment that enteric coated tablets are subject to.24 Further studies in human subjects demonstrating the difference in IVIVC between enteric and non-enteric coated tablets could not be identified in the literature. There are hundreds of other drugs which have an IVIVC and these are neither limited to BCS class II drugs or drugs with dissolution rate limited absorption. Theophylline is a BCS class IV drug and yet in a complete cross over study of four different theophylline tablets the in vitro dissolution was able to significantly predict several in vivo pharmacokinetic parameters (AUC Cmax) which dictate bioavailability.25 The study was small (n = 6) and not all pharmacokinetic parameters could be correlated. Other common drug examples with IVIVC include digoxin,26 rifampicin,27 diclofenac28 and lamotrigine29 and these are by no means exhaustive. 5.2.2 Drugs without IVIVC Not all drugs have an IVIVC and this can also include some BCS class II drugs. A research paper by Frick, Moller Wirbitzki 199830 demonstrated that the in vitro dissolution of glimepiride (BCS class II) is not comparable to dissolution in vivo. The study employed a single dose cross-over design with 12 subjects, Latin-Square statistical analysis was employed and the results were assumed to be significant however not all the data was accompanied by supporting confidence values. No correlation was possible because the solubility of glimepiride is low and strongly pH dependent.30 Unlike glimepiride, ciprofloxacin a quinolone antibiotic, is classified as a BCS class III drug and as a consequence would not be predicted to have an IVIVC. Correspondingly, when tested for this possibility none could be found between dissolution and any of the parameters for bioavailability (Tmax, Cmax, AUC Ka).31 5.2.3 Strength of BCS in predicting IVIVC There is a wide variance between IVIVCs that are anticipated according to the BCS and those that are actually demonstrated after experimental testing. Examples have been provided where both expected and unexpected correlations occur and this suggests that the BCS system while helpful should only be taken as a guide. Laboratory testing is still the only reliable method for determining if a correlation is occurs. Paracetamol is a BCS class III medication and as such is not expected to demonstrate strong IVIVC. Given the fact that paracetamol has a wide therapeutic index and the BCS can only be used as a guide, a safe and useable IVIVC may still exist. 5.2.4 IVIVC of paracetamol The prodigious use, vast quantities manufactured and the presence of many generic products in the marketplace makes paracetamol a prime candidate for IVIVC testing. In 1996 Retaco et. al.32 conducted a small crossover study using five subjects to assess whether an IVIVC for paracetamol may exist. The study stated that the absorption data from saliva partially correlated with those found in vitro,32 this however is not a valid conclusion. One of the subjects studied produced in vivo data that opposed a correlation and this anomaly was further confounded by the fact that statistical analysis was not performed on the IVIVC but rather covered the in vitro and in vivo data separately. This pilot study was later contradicted by Babalola et. al.33 who found limited IVIVCs and suggested that paracetamol absorption may not be limited by its dissolution rate. Similarly, a thorough, well designed, complete crossover (44) study that balanced for first order residual effects, suggested that it wa s dangerous to use dissolution as the sole test for paracetamol bioequivalence.34 Interestingly, all of these studies demonstrated bioequivalence between the various products of paracetamol even if they showed no IVIVC. 6 Biowaiver for bioequivalence testing In vivo bioequivalence studies are required to ascertain the potential differences in bioavailability between innovator and generic products which, may lead to therapeutic inequivalence. A biowaiver provides the authority and grounds for fiscally intensive bioequivalence testing to be replaced by more tolerable in vitro testing. For the most part, IVIVC must first be established in order for a drug to be considered for a biowaiver. The BCS has outlined properties of solid preparations which require evaluation in biowaivers, i.e. solubility, permeability, and dissolution rate.35 In addition to this, the non-critical therapeutic range of a drug should also be considered35 and this is the basis for which paracetamol has gained biowaiver status.3 It should be noted that products produced by the same manufacturer at the same site are exempt from bioequivalence studies.36 6.1 Paracetamol Biowaiver Several characteristics must be considered when a drug presents as a candidate for a biowaiver through dissolution testing. Paracetamol is not a classic biowaiver candidate because it is classified as a BCS Class III drug, it does however possess properties borderline to Class I3 and these enable it to fulfill the requirements of a biowaiver. 6.2 Biowaiver requirements 6.2.1 Characteristics relevant to the active ingredient 6.2.1.1 Risk of therapeutic failure or adverse drug reactions i.e. the need for critical plasma concentrations. When considering a biowaiver for a drug substance, its therapeutic use and therapeutic index also needs to be taken into account.16 In the case of paracetamol, the therapeutic indications are not critical, and there is a wide difference between the usual therapeutic dose and toxic doses. Given that an optimal therapeutic dose for an adult is 1g, and that hepatocellular necrosis can result from ingestion of 10-15g, it can be assumed that paracetamol is not a narrow therapeutic index drug.3 6.2.1.2 Risk of bioinequivalence: Previous evidence of bioavailability problems for an active substance can complicate the justification of in vitro dissolution bioequivalence correlation.35 For paracetamol, the absolute bioavailability has not been shown to vary between therapeutic dose ranges of 5-20mg/kg.3 Other studies have also demonstrated that bioequivalence in different IR paracetamol preparations is achievable.11, 32, 37 6.2.1.3 Solubility: If a drug is highly water soluble it generally lends to exemption of bioequivalence testing, however polymorphism and particle size are major determinants of dissolution and must be considered.35 A drug is considered highly soluble if the amount contained in a preparation of maximal strength dissolves in 250mL of three buffered solutions ranging between a pH of 1-8 at 37C.35 Paracetamol has a pKa of 9.5 and is therefore not substantially ionized at a pH less than 9. As a result, it can be said that its solubility does not vary with pH.3 The highest strength IR preparation of paracetamol is 500mg. Experimentally, this has been shown to dissolve in 21mL,3 which is significantly less than the 250mL that is required by the BCS guidance to prove solubility.16, 35 6.2.1.4 Pharmacokinetic properties: High permeability which is typically indicated by a linear absorption pattern, reduces the potential influence of an IR preparation on bioavailability.35 For paracetamol, the permeability is slightly below the cut-off value of 90%, i.e. one study by Stewart et al.38 found permeability to be 80% once absorbed. This formally excludes paracetamol from being considered for a biowaiver, although extensions to BCS Class III drugs have recently been given more attention.20, 39 6.2.2 Characteristics relevant to the medicinal product 6.2.2.1 Rapid dissolution: Dissolution profiles can be regarded as equal when more than 85% of the active ingredient is dissolved within 15 minutes.35 This comparison must occur between test and reference product in three buffers which with a pH range between 1-8, at 37C.35 Paracetamol tablets have been shown to dissolve within 30 minutes,32 however this rate does not satisfy BCS exemption standards. 6.2.2.2 Excipients: Those included are to be well established and not in atypically large quantities. Kalantzi et al.3 details a table of acceptable excipients which can be used within paracetamol IR tablet formulations which are considered for in vitro dissolution biowaiver. 6.2.2.3 Manufacture: Critical parameters such as particle size and polymorphism should be addressed and documentation should be provided in the dossier that is submitted to TGA.35 Paracetamol has three metastable forms, the only commercially available from is the monoclinic acetaminophen as it is the most thermodynamically stable polymorph.3 From review of the literature, it can be concluded that in vivo bioequivalence testing of solid, oral IR paracetamol dosage forms may not be necessary. This can be justified given that a paracetamol formulation can be shown to:3 Rapidly dissolve under USP guidelines Contain only the acceptable excipients, in usual quantities Demonstrates dissolution profile similar to reference product under conditions stated in USP guidelines 7 Statement of Purpose 7.1 Aim hypothesis The purpose of the proposed study is to compare the dissolution profiles of bioequivalent IR paracetamol preparations listed on the PBS. In particular, comparisons between every preparation will be made, rather than a single comparison against a referent. We hypothesize that there will be no significant difference between the dissolution profile of IR paracetamol tablets when dissolved according to USP specifications. 7.2 Methodology We propose to analyse the dissolution profiles of eight PBS listed bioequivalent paracetamol preparations, namely; APO-paracetamol, Chemmart Paracetamol, Dymadon P, Febridol, Panamax, Paracetamol Sandoz, Paralgin, and Terry White Chemists Paracetamol. Sixteen tablets of each preparation will be dissolved in compliance with USP dissolution test for tablets and capsules, using apparatus II. As mandated, tablets are to be dissolved in 900mL phosphate buffer at a pH of 5.8 with a paddle set to 50rpm. Samples will be taken at intervals of 2,5,10,15,30,45,60 minutes in concordance with practice by Dominguez et al.34 these aliquots will be examined for paracetamol by UV spectrophotometry at 289nm. These data will be statistically analysed by ANOVA. 7.3 Timeline Date Tasks to be performed Work Deadlines Week 11 (15.03 21.03) Create paracetamol standard curves, Test expected dissolution time, Order materials, Source test tablets, Visit school of statistics for advice. Literature Review Due Monday 15th March 12pm Week 12 (22.03 28.03) Testing of tablets 1 2: Dissolution UV vis Week 13 (29.03 04.04) Testing of tablets 3 4: Dissolution UV vis Week 14 (05.04 11.04) Testing of tablets 5 6: Dissolution UV vis Week 15 (12.04 18.04) Testing of tablets 7 8: Dissolution UV vis Week 16 (19.04 25.04) Week in lieu to finish experiments in case of unforeseen circumstances Week 17 (26.04 02.05) Data collation statistical analysis Briefing on the writing of the final report Wed 28.04 2pm Week 18 (03.05 09.05) Writing draft report Week 19 (10.05-16.05) Editing final draft report Week 20 (17.05 23.05) Powerpoint presentation format 1st Draft Research Project Due Friday 21st May Week 21 (24.05 30.05) Correcting draft report Week 22 (31.05 06.06) Amending powerpoint presentation Final report due Mon 31.05 12pm Week 23 (07.06 13.06) Amending final report Week 24 (14.06 20.06) Presentation rehearsal Seminars, submission of amended report to pharmacy office

Mental Capacity and Informed Consent to Receive Treatment

Mental Capacity and Informed Consent to Receive Treatment Legal, Ethical and Professional issues surrounding mental capacity and informed consent to receive treatment Throughout this essay, we will be reviewing and discussing the legal, ethical and professional issues associated with two key aspects of paramedic practice, these are mental capacity and the ability to provide informed consent to treatment and intervention. As the title suggests, the essay will be broken down into three separate sections which will individually relate to the topics in hand. The legal section will focus on how legislation affects the two stated aspects. The professional aspect will cover how mental capacity and informed consent can create professional issues for the paramedic, whilst the final part of the essay will focus on relating the four principles of ethics to the topics which are discussed in this essay. The regulator for Paramedics, the Health Care Professions Council (HCPC) sets out standards of conduct, performance and ethics which states that you must make sure that you have consent from service users or other appropriate authority before you provide care, treatment or other services (HCPC, 2016). There are four principles of ethics will be related to throughout the essay and explanations for these principles are found in appendix A of the essay (UKCEN, 2011). Legally, it is always necessary to seek informed consent before beginning treatment and intervention, except in certain circumstances which will be detailed later in this essay. The department of healths guidance on consent states that consent is a general, legal and ethical principle which must be obtained before starting treatment or physical investigation (Dept. of Health, 2009). If a clinician were to being treatment/care without the informed consent of the patient, the patient may be able to present a case of battery against the clinician. Most cases where the clinician has failed in the process of gaining consent have been due to not thoroughly explaining risks; this can lead to medical negligence as the recipient of care would not be expecting the associated risks. (Laurie et al, 2016). In legislation in the United Kingdom, there is a standardised examination called the Bolam Test which needs to have its criteria fulfilled in order to prove that medical negligence has taken pl ace. The Bolam test involves a group of peers from the same profession as the clinical reviewing the procedure which the patient may see as being negligent (The Royal College of Surgeons of England, 2016). In terms of the paramedic profession, the regulator will provide peers in order to conduct the Bolam test (HCPC, 2016). In some situations, it is very difficult to gain consent before beginning patient treatment, this can be for various reasons such as the patient being unconscious. In this situation, Paramedics/Healthcare providers are able to use the doctrine of necessity which allows them to provide initial life-saving interventions in order to save life/limb when the individual receiving the care is unable to provide informed consent (Hartman K, et al, 1999). The Mental Capacity act 1983 provides the main legal basis for providing guidance and regulation on whether an individual over the age of eighteen would be seen to have or lack mental capacity, it defines a person who lacks capacity as a person who at the time of assessment is unable to make a decision for himself in relation to the matter because of an impairment of, or a disturbance in the functioning of, the mind or brain. (Mental Capacity Act, 2005). The Mental Capacity act was created to safeguard and give power to individuals which may lack the capacity to make informed decisions about care and treatments (Brown M, 2014). The legislation in place provides clear guidance on how to safely identify when an individual lacks capacity and the rights of the individual which lacks capacity. Paramedics use a standardised approach when assessing whether an individual lacks mental capacity, this is known as the two-stage test of capacity (Dept. of Constitutional Affairs, 2007). The first stage of the test involves investigating whether there is cause to believe that there is an impairment in the function of the individuals cognitive functioning. There are many different reasons why there may be a disruption in the functioning of the mind, which can include but is not limited to: Dementia, Head injury, Stroke, Intoxication and learning difficulties (Dept. of Constitutional Affairs, 2007) . Stage two of the mental capacity assessment requires the clinician to evaluate whether the disturbance outlined from stage one causes the individual to be unable to make a specific decision with regards to their treatment, this is assessed by providing the individual with information regarding their condition and then asking them to repeat it at a later time so that the clinician is confident the patient is able to retain the information (Dept. of Constitutional Affairs, 2007). The Mental Capacity Act 2005 contains five principles which underpin the act and must always be applied i n the process of evaluating whether an individual may lack capacity, the five principles are explained in more detail in appendix B. Ethically, when a patient is deemed to not lack capacity, they are then in a position where they may be able to provide informed consent to treatment. For the patient to have informed consent they must have received or have the four components needed to make informed consent. The patient must have the capacity to make the decision. The Paramedic must fully explain the treatment, the side effects of the treatment, the risks of having the treatment and the risks of not having the treatment whilst also explaining the probability of said risks occurring. The patient must fully understand the information that has been given to them by the Paramedic and the patient must then voluntarily give consent to treatment without coercion from a third party such as a relative, friend, or the health care provider (David, 2010). In healthcare, the idea of consent may be sometimes misunderstood as doing what the doctor says which, in modern days, is not the case. There has been debate as to whether con sent was sought in the past, due to the fact the patient placed trust in the physicians beneficence (aim to reduce harm to the patient) and non-maleficence (doing no harm to patients intentionally) and therefore trusted in what the clinician was doing (Habiba, 2000). Beneficence and non-maleficence are two of the four ethical principles. The assessment of whether someone lacks mental capacity is vital in the Paramedics ability to use alternative pathways and referral systems. As Paramedics are highly skilled, autonomous practitioners and work in a variety of out-of-hospital areas, such as public places, patients own homes, and residential care settings, it sometimes proves more relevant to discharge patients from care on scene (Ball, 2005). To do this safely, in a way which will cause no further harm for the patient, the patient must have mental capacity to make their own decisions regarding their care and treatment. The key definition of mental capacity comes from the Mental Capacity Act (2005) which states that capacity is the ability of an individual to make their own decisions regarding specific elements of their life (Mental Capacity Act, 2005). Patients are only able to give informed consent to treatment/intervention if they have mental capacity and therefore it is imperative that Paramedics can effectively ass ess whether a patient lacks capacity. In assessing whether an individual lacks mental capacity, the paramedic is showing respect for the patients autonomy which is one of the four ethical principles. In terms of professional issues, the ability to provide informed consent can seriously affect the way in which Paramedics treat and advise patient. An example of this comes from a 2009 case in which an individual drank anti-freeze and then presented the ambulance crew with a letter, clearly stating that she did not consent to lifesaving intervention but did consent to analgesics in order to comfort her. Through the letter (which can be read and has been annotated in appendix C), the individual displayed she had full mental capacity to make her own decision and also accepted the responsibility for the outcomes of not receiving care (Armstrong W, 2009). In the context of a time critical situation where a decision would need to be made with regards to giving lifesaving saving intervention and withholding it, it can be sometimes difficult for the Paramedic to gather sufficient evidence that the patient (who may lack mental capacity) has created a living will, or that there is an advanced decision to refuse treatment (ADRT) put in place which clearly outlines the patients wishes (what they do and do not consent to) when it comes to end of life care. In the absence of this (or absence of any evidence of this) ambulance staff may be forced to act in the patients best interests. In the context of ambulance staff, the best interests of the patients may be difficult to decide as very little background may be available to the attending paramedic, however if the health care professional is unaware of any ADRT and has taken all reasonable steps in the time available to discover whether an ADRT is in place in the time frame available to them, the clinician making the decision will be protected from liability (Dept. of Constitutional Affairs, 2007). The HCPC states in their standards of conduct, performance and ethics that competent individuals have the right to refuse treatment and that this right must be respected (HCPC, 2016). Whether an individual is deemed to lack or have capacity can sometimes present similar professional issues to informed consent in terms of paramedic practice. For the individual who lacks capacity, it can be a very stressful time as they may be confused, disorientated or feel as though they have little control over what is happening to them. The Mental Capacity Act states that nobody has the right to deprive someone of their liberty except in situations where they lack capacity and it is necessary to give life-sustaining treatment or to prevent a serious deterioration in their condition. In this situation, any restraint used must be proportionate to the risks to the person from inaction (Mental Capacity Act, 2005). There are no additional rights or authority for paramedics to act in this situation, but if there was cause to believe that there was serious risk to an individuals life and that they lacked capacity, it would be within the Paramedics rights to act in such a way to protect the individual from further harming themselves or provide life sustaining treatment in the event of lack of capacity. Furthermore, the standards of conduct, performance and ethics provided by the health care professions council states that registrants must take all reasonable steps to reduce the risk of harm to service users (HCPC, 2016), therefore if a registrant were to stand aside and allow an individual who lacked capacity to cause harm to themselves or to further deteriorate, they may be at risk of committing an act of omission or even committing wilful neglect which can constitute a criminal offence. In conclusion, the professional issues surrounding informed consent and mental capacity are applied in every single incident a paramedic may attend and are closely linked. A failure to recognise a lack in mental capacity or gain informed consent may cause detrimental legal and professional repercussions for both the clinician and service user. Although Paramedics are able to seek further advice from sources such as the local police force, senior members of ambulance staff, and general practitioners in order to safeguard their practice, a good working knowledge of the policies and procedures surrounding the issues mentioned in this essay will provide a good basis for gaining informed consent, the assessment of mental capacity and management of service users who lack capacity in the pre-hospital urgent care environment. Reference List Armstrong W, (2009) Kerrie Wooltorton Inquest Held 28 September 2009 Notes of Extracts From Summing Up By Coroner William Armstrong HM Coroner Norfolk District (page 1) Ball L . (2005). Setting the scene for the paramedic in primary care: a review of the literature. Emergency Medicine Journal. 22 (12), p896-900. Brown M. (2014). Should we change the Mental Health Act 1983 for emergency services?. British Journal of Mental Health Nursing. 3 (3), P114-115. Department for Constitutional Affairs. (2007). Mental Capacity Act 2005 Code of Practice. Available: https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/497253/Mental-capacity-act-code-of-practice.pdf. Last accessed 11th Mar 2017. Department of Health (2009). Reference guide to consent for examination or treatment. London: Her Majestys Stationary Office. Habiba, M. (2000). Examining consent within the patient-doctor relationship. Journal of Medical Ethics. 26 (5), p183-187. Hartman K, Liang b. (1999). Exceptions to Informed Consent. Hospital Physician. 6 (3), p53 59. Health and Care Professions Council. (2016). Standards of conduct, performance and ethics. Available: http://www.hcpc-uk.org/assets/documents/10004EDFStandardsofconduct,performanceandethics.pdf. Last accessed 1st Mar 2017. Health Care Professions Council. (2016). What happens if a concern is raised about me?. Available: http://www.hpc-uk.org/assets/documents/100008E2HPC_What_happens_if.pdf. Last accessed 8th Mar 2017. Laurie GT, Harmon HE and Porter G (2016). Mason and McCall Smiths Law and Medical Ethics (10th Edition). Oxford University Press. Oxford. Mental Capacity Act (2005) . Available: http://www.legislation.gov.uk/ukpga/2005/9/section/2. Last accessed 11th Mar 2017. Sibson, L. (2010). Informed consent. Journal Of Paramedic Practice. 2 (5), p189. The Royal College of Surgeons of England. (2016). Consent: Supported Decision-Making. London: Professional and Clinical Standards. UKCEN. (2011). Ethical Frameworks. Available: http://www.ukcen.net/ethical_issues/ethical_frameworks/the_four_principles_of_biomedical_ethics. Last accessed 13th Mar 2016. Appendix A The four principles of medical ethics Respect for autonomy This principle involves respecting the decision-making capabilities of the service users and providing reasonable assistance in order to make informed choices regarding their care. Beneficence This principle considers the weighing up of the associated risks and costs of treatments against the benefits and likely outcomes. Paramedics should always aim to act in a way which benefits the patient Non-maleficence This principle surrounds the need for paramedics and other health care professionals to avoid causing harm to the individual. Although all treatments involve some level of harm, this should not be disproportionate to the benefits which are as a result of intervention. Justice This principle is about distributing treatments available to each individual fairly and not favouring one service user over the other by means of extra treatments/intervention. UKCEN, 2011 Appendix B The Five Key Principles of the Mental Capacity Act Presumption of capacity This principles states that an individual adult should always be presumed to have full mental capacity until they are proven otherwise. A presumption of capacity should not be made as a result of an individual having a certain medical condition or disability. Individuals being supported to make their own decisions This principle states that individuals should be supported in every possible way to make their own decision before they are deemed to lack capacity. It also means that if it is deemed the individual does lack capacity that they should still be involved in the decision-making process. Unwise decisions This principle states that the individual has the right to make unwise decisions and that the assumption the person lacks capacity should not be made based on a decision. This is due to a difference in cultural values, beliefs and preferences. Best interests This principle states that an individual who lacks capacity is entitled to the decisions which are made on their behalf are done solely in their best interests Less restrictive option This principle states that the individual who makes decisions on behalf of the incapacitated person must make decisions which will have the least effect on the individuals rights and freedoms. Mental Capacity Act, 2005 Appendix C Kerrie Wooltorton Advanced Decisions Letter Armstrong W, (2009)Â  

The Life of William Shakespeare Essay examples -- Shakespeare

William Shakespeare was a very talented man known for his various works of literature. His works include poems, plays, and sonnets. His works are then broken down into tragedies, comedies, and histories. Shakespeare left this world centuries ago, but his writings continue to live throughout the world today. He has greatly impacted the world of literature and his existence will forever be remembered. In 1564, William Shakespeare was born in Stratford-upon-Avon (Hazell 32). It seems that Shakespeare’s career began around the year 1592. This was a tough time for playwrights and actors. There was an outbreak of the bubonic plague which caused concerns for those wanting to watch because of being surrounded by those potentially carrying the disease, thus making it hard for the playwrights and actors to find work (â€Å"William Shakespeare.† 653-654). Not only was disease an obstacle William Shakespeare had to overcome in his work, he was also forced to face hampering from religious aspects as well. Leaders in the Puritan community looked down upon plays, acting, and other things of that nature. These authorities thought that these activities would sway people from focusing on the importance of practicing their religion. Plays and such were not allowed to be performed while in the city of London. They were banned. Eventually, despite all the obstructions, plays and theater came to be a popular thing although still forced outside the city (â€Å"The Changing Status...†). After overcoming the troubles of becoming an actor and a playwright, William Shakespeare has become well renowned. His works reach to people all around the world despite the language barriers and different races and cultures. For centuries, the popularity of his work... ... Co., 1919. 5. Print. Ellis, Jessica. â€Å"What are Shakespeare’s Comedies?† wiseGEEK. Conjecture Corp., 2003. Web. 31 Jan. 2012. Frye, Roland Mushat. Shakespeare’s Life and Times. Princeton, NJ: Princeton University Press, 1967. 16. Print. Hazell, Rebecca. Heroes: Great Men Through the Ages. New York: Abbeville Press, N.d. 32. Print. McMillan, Eric. â€Å"Who Was the Greatest of All Writers?† The Greatest Authors of All Time. N.p. 2011. Web. 26 Jan. 2012. â€Å"Race – Introduction.† Shakespearean Criticism. eNotes.com. Gale Cengage, 2006. Web. 31 Jan. 2012. Schwartz, Debora B. â€Å"Shakespeare’s Plays: The Histories.† ENGL 339. N.p. 2002. Web. 31 Jan. 2012. â€Å"The Changing Status of Theater.† About.Com.Shakespeare. The New York Times Co., 2012. Web. 31 Jan. 2012. â€Å"William Shakespeare.† Encyclopedia Americana. Vol. 24. Danbury, CT: Grolier Inc., 1994. 652-654; 656. Print.

Macbeth vs Scotland, PA Essay -- essays research papers fc

Macbeth: The thin line between tragedy and dark humor. William Shakespeare’s Macbeth has always been considered one of the literary worlds most celebrated tragedies. It is arguably the darkest and most gruesome of his plays. The protagonist, Macbeth, is the poster child for tragic hero, â€Å"a literary character who makes an error of judgment or has a fatal flaw that, combined with fate and external forces, brings on a tragedy† (www.dictionary.com). And until recently we were satisfied with that†¦ At the Cannes Film Festival in 2001, a low budget comedy was unveiled. It was called Scotland, PA. This film was written by a first-time director, Billy Morrissette, and depicts the familiar story in a surprisingly different form. The premise of the plot is held in tact but the setting is shifted several hundred years, to the 1970s. The characters’ names even remain familiar. The dialogue is contemporary English yet you can still recognize the similarities in conversation. Major themes from the original work – revenge, guilt, self doubt, fate, and prophecy still exist in this manipulated adaptation. â€Å"He (Morrissette) is able to make an interesting point about how the difference between tragedy and comedy is often how the material is viewed by the audience†.(Berardinelli) Prior to Morrissette’s Scotland, PA, Roman Polanski brought his adaptation of Macbeth (1971) to the silver screen. This more traditional adaptation follows the plays blueprint. The setting remains unchanged, as well as the plot and dialogue. This movie was made soon after a horrifically traumatic events in Polanski’s life, the heinous murder of his pregnant wife by members of the ‘Charlie Manson family’. The film may have been a therapeutic outlet for him. The extremely gory murder scenes may have been a result of his attempts to deal with his pain and show give insight into the horror that filled his life at the time. Polanski’s adaptation definitely added a horror flick tone with the gruesome portrayal of despicable violence. The most notable difference in the portrayal of Mac and Pat, in Scotland, PA versus the portrayal of Macbeth and Lady Macbeth, in Macbeth, is the atrociousness, or lack of, with which we view them and their crimes. Mac and Pat seem to be less despicable than Macbeth and Lady Macbeth for several reasons. One key reason is the omission of the ordered murder of Macduff’s family ... ...ind their evil deed. Lady Macbeth is aware of her position as motivator, and even states in the play that she wishes she were a man so that she could carry out their plan herself. Even in Scotland, PA, Pat is continuously directing and instructing Mac in all of their actions pertaining to the murder and cover up. She tells Macbeth to get the safe combination, to stop him from escaping, and talks him through virtually the entire process. The major difference in the two works is presentation and context. This relates directly to the representation of the main characters. By keeping the premise but altering the way the course of events occurs gives the audience a different insight into the development and representation of the characters, particularly Macbeth and Lady Macbeth. Both adaptations were very well done, particularly Scotland, PA. It shows that, with a little tweaking, comedy can be found in even the most bloody and tragic of stories. Works Cited: Dictionary.com. 2005, Lexico Publishing Group, LLC. 3/8/2005 . Macbeth [1971] – Review @ EOFFTV. 2000, 3/8/2005 . Phillips, Brian and Douthat, Ross. SparkNote on Macbeth. 9 Mar. 2005 . Review: Scotland, PA. 2002, 3/8/2005 .

The Cultural Identity Within Asian Writing Systems Essay -- Cultural Id

The Cultural Identity Within Asian Writing Systems The style of Asian writing seems to be completely different from that of the western writing systems. For starters, many western languages are phonetic: words are spelled out with symbols that represent sounds. The way that a word looks has nothing to do with the meaning of the word. On the other hand, the most recognized form of Asian writing, Chinese characters, are completely pictographic. A single character is correlated to one sound or meaning. To convey more complicated meanings, pictographs are either combined into new pictographs, or multiple characters are simply used in succession. The meaning of words is depicted through pictographs, but for the most part, there is no information about their pronunciations. Asian and western languages appear so different because they had evolved in isolation from each other for hundreds of years. However, the evolution of each group of languages is similar. Whether Asian or western, languages borrow from each other and evolve toge ther when they are in close quarters. Chinese, Japanese, and Korean are perfect examples of languages that have evolved together because they are spoken in countries that are so close together. Their cultures are also arguably similar when compared to western cultures. All three have used Chinese characters exclusively as their writing system for a period of time and parts of the Korean and Japanese vocabularies are actually derived from Chinese. Up until a few hundred years ago, the three written languages have developed quite closely. But in the present day, the three systems appear to have taken very different evolutionary paths. The Korean language has developed a phonetic alphabet syste... ...se Writing System. 20 July 2001. Kanji Dictionary Publishing Society. 20 Apr. 2004 <http://www.kanji.org/kanji/japanese/writing/outline.htm>. Katsiavriades, Kryss. KryssTal:Language Page. Amazon, Britannica. 20 Apr. 2004 <http://www.krysstal.com/language.html>. Laugk. "Chinese hostages to their writing system: A case for simplification and reform." China Daily 7 Feb. 2004. 20 Apr. 2004 <http://www.chinadaily.com.cn/english/doc/2004-02/07/content_304083.htm>. Noll, Paul. History of the Chinese Language. 25 Mar. 2004. 20 Apr. 2004 <http://www.paulnoll.com/China/Culture/language-history.html>. Ohak-Yonku. "Formation of Korean Alphabet." Language-Research Sept. 1987: 527-537. "Types of Writing Systems." AncientScripts.com. 20 Apr. 2004 <http://www.ancientscripts.com/ws_types.html>. Usaburo, Shimizu. "Hiragana." Meiroku Zasshi 1800s.

Essay About Literature Essay

Literature is timeless, it endured all the changes of the past and is still is being appreciated till the present time and will still be as time goes by.  Literature exists in every country, in every language, and in every period but each has its own uniqueness that stands out for their styles. It exceeds time; literary works of famous people regardless of what period in time they came from is still being appreciated, if not more than when the period it is from. Literary works from the early periods had undergone different adaptations by the later periods to preserve the author’s great work, the ideas, and the creativity they instil in every words to make it live through time. There is a purpose for reading literary works – to entertain and educate its readers or audience. Reading, for example, a novel is just like watching a movie in a very slow pace; reading can make you cry, laugh, smile, get angry and whatnot just like watching a movie; reading lets us imagine the characters, the settings, and what happens in the story. As it entertains us, it also educates us and teaches us about life experiences that we might encounter, and the morals that we should possess. Other literary works inform us about happenings in daily life which also falls in educating the readers. There are different types of literary works, it doesn’t just end with reading materials, and it can also be in a form of a song and a play. It can be performed in front of people or just enjoyed by oneself; it has different genres to offer to different interests of people. Literature is everywhere and in any time and it knows no bounds.

Iroquis Theater

battlefield Fire changed the steering we in a flash regulate engraves for more buildings. Some codes that were through ascribable to the free ar explained soundly in this paper. Two online articles were used to salvage the paper. Iroquois Theatre Fire could obligate been pr scourted, still due to what happened at the battlefield we instanter grow mandatory codes every humanity building must follow onwards opening, making patrons unassailable. Rushing the twisting was a bad decision filling the theatre above Its capacity as an even worse mistake.Government officials make sure all(a) these new regulations were followed through aft(prenominal) the go up. On a Wednesday afternoon a go off that would change the codes for galore(postnominal) domain buildings happened at Iroquois Theatre. Many masses called the theatre p detonator, but that wasnt the case that Monday afternoon. While many people watched the second act of a play, the tone-beginning started. A spark from a malfunctioning light ignited a drop curtain and it spread quickly catching thousands of square feet on conjure.Due to ruddier construction to open the theatre right away, roof vents had been sealed off, preventing the heat, smoke and gases from escaping the fire causation many people to die. A fire curtain was supposed to be move in case of fire, but the stagehand trained to do so was bulge sick. These made many government officials infer of how codes are important to prevent many deaths, or a fire. Reasons why we restrain exit signs on top of exits were because of the Iroquois Theatre Fire.Iroquois Theatre Fire caused 602 lives to leave to nirvana when a fire like that could take up been prevented y many ways. Many law, regulations, and codes were made due to this fire, which changed our lives. Due to these regulations a fire can be handled the right way and people can go about step to the fore of buildings faster. A regulation that is mandatory for buildings to baffle now is an exit sign on top of doors and clearly marked, and operable easily. In the theatre fire there was fire exits, but were either obstruct or not marked to keep go forth unpaid patron go forth.Now fire exits are mandatory to be in a building and clearly marked. At the clock time fire sprinklers were a new thing, due to the rushed construction the theatre didnt have them, fire sprinklers are now a mandatory for theatre stages. It Is said the sprinklers could have raised the chances of this fire spreading as fast as It did, now buildings arent forego to open If fire sprinklers arent In the ceiling. The urban center of Chicago also rewrote its fire code to mandate outward-swinging doors In theaters, which now makes it safe for people to walk out of places In case of a fire happening.A clank bar was made for all public buildings doors making It easy to run out of a building. On that night after workers couldnt extinguish the fire people started to go crazy and could nt get out. All doors were blocked as people were trying to get out, due to having more people than the line of work allowed. Since doors were blocked people stomped on individually other to force their way out. The fire wasnt the reason why many deaths happened, people stomping on each other killed many to the people.